Genetic testing of embryo ( PGT)

🧬 Genetic Testing of Embryos (PGT)

Building Healthy Beginnings – One Cell at a Time

Preimplantation Genetic Testing (PGT) is an advanced technique used during IVF to screen embryos for genetic abnormalities before implantation. It helps select the healthiest embryos, increasing the chances of a successful pregnancy and a healthy baby.

🔍 Types of PGT

1. PGT-A (Aneuploidy Testing):

   • Checks for abnormal number of chromosomes (like Down syndrome, Turner syndrome)

   • Helps select embryos with the correct chromosome count

   • Recommended for:

     • Women over 35

     • Recurrent miscarriages

     • Repeated IVF failures

2. PGT-M (Monogenic/Single-Gene Disorders):

   • Screens for inherited genetic conditions (like Thalassemia, Cystic Fibrosis, Sickle Cell Anemia)

   • Ideal for couples who are known carriers of a genetic disorder

3. PGT-SR (Structural Rearrangements):

   • Detects chromosome rearrangements like translocations or inversions

   • Useful when one partner has a known chromosomal issue

🧫 How Is PGT Done?

1. IVF is performed to create embryos

2. On Day 5 (blastocyst stage), a few cells are safely biopsied from each embryo

3. Biopsied cells are sent to a genetic lab for analysis

4. Embryos are frozen while results are awaited

5. Only healthy embryos are selected for transfer in a later cycle

✅ Benefits of PGT

• Higher chances of pregnancy

• Lower risk of miscarriage

• Reduces need for multiple IVF cycles

• Helps avoid passing on serious genetic diseases

• Improves implantation rates, especially in older women

⚠️ Things to Consider

• Adds cost to the IVF cycle

• Requires embryo freezing (FET cycle)

• May slightly reduce the number of usable embryos

🌈 Who Should Consider PGT?

• Couples with known genetic diseases

• Women over 35 years of age

• History of repeated IVF failures

• Recurrent pregnancy losses

• Male partner with abnormal karyotype

PGT gives your little one the healthiest start possible.
It’s science, safety, and hope—working together for your future family. 💕